Dr. Chuang's Google Scholar Profile
Full list of publications on PubMed
2024
Siete C. †, Xiong, R. †, Khalid, A.*, and Chuang, C.-F. (2024). Immobilization of C. elegans with different concentrations of an anesthetic for time-lase imaging of dynamic protein trafficking in neurons. microPublication Biology. 10.17912/micropub.biology.001069.
†These authors contributed equally to this work. *UIC undergraduate student.
2022
Xiong, R.†, Hsieh, Y.-W.†, and Chuang, C.-F. (2022). CEPsh glia development is not required for general AWC identity or AWC asymmetry. microPublication Biology. 10.17912/micropub.biology.000529.
†These authors contributed equally to this work.
Xiong, R., Hsieh, Y.-W., and Chuang, C.-F. (2022). mNG-tagged mls-2 knock-in alleles in C. elegans. microPublication Biology. 10.17912/micropub.biology.000529.
Hsieh, Y.-W. and Chuang, C.-F. (2022). Analysis of unc-62 expression pattern in C. elegans embryonic AWC neurons. microPublication Biology. 10.17912/micropub.biology.000530.
2021
Hsieh, Y.-W.†, Xiong, R.†, and Chuang, C.-F. (2021). Synergistic roles of homeodomain proteins UNC-62 homothorax and MLS-2 HMX/NKX in the specification of olfactory neurons in Caenorhabditis elegans. Genetics 219(2). doi: 10.1093/genetics/iyab133.
†These authors contributed equally to this work.
2019
Alqadah, A., Hsieh, Y.-W., Xiong, R., Lesch, B.J., Chang, C., and Chuang, C.-F. (2019). A universal transportin proteindiversifies olfactory neurons via specific nuclear import of a sox-2-activating factor. Proc. Natl. Acad. Sci. 116, 25137-25146.
2018
Chiu, H., Zou, Y., Suzuki, N., Hsieh, Y.-W., Chuang, C.-F., Wu, Y.-C., and Chang, C. (2018). Engulfing cellspromote neuronal regeneration and remove neuronal debris through distinct biochemicalfunctions of CED-1. Nature Communications 9. doi: 10.1038/s41467-018-07291-x.
Alqadah, A., Hsieh, Y.-W., Morrissey, Z., and Chuang, C.-F. (2018). Asymmetric development of the nervous system. Invited review for the special issue on development, disease and repair of the nervous system. Developmental Dynamics 247, 124-137. doi: 10.1002/dvdy.24595.
2017
Hsieh, Y.-W., Alqadah, A., and Chuang, C.-F. (2017). Mechanisms controlling diversification of olfactory sensory neuron classes. Invited review for Cellular and Molecular Life Sciences. doi:10.1007/s00018-017-2512-2.
Oh, K.H., Haney, J.J., Wang, X., Chuang, C.-F., Richmond, J.E., and Kim, H. (2017). ERG-28 controls BK channel trafficking in the ER to regulate synaptic function and alcohol response in C. elegans. eLife 2017;6:e24733. doi: http://dx.doi.org/10.7554/eLife.24733
2016
Hsieh, Y.-W., Alqadah, A., and Chuang, C.-F. (2016). An optimized protocol for electrophoretic mobility shift assay using infrared fluorescent dye-labeled oligonucleotides. Journal of Visualized Experiments 117: e54863. doi:10.3791/54863
Alqadah, A., Hsieh, Y.-W., Xiong, R., and Chuang, C.-F. (2016). Stochastic left-right neural asymmetry in C. elegans. Invited review for the special issue on left-right asymmetries of pattern formation: integrating chiral information from cells to organisms. Philosophical Transactions of the Royal Society B 371: 20150407. doi: 10.1098/rstb.2015.0407.
Alqadah, A., Hsieh, Y.-W., and Chuang, C.-F. (2016). Sox2 goes beyond stem cell biology. Cell Cycle 15, 777-778, doi: 10.1080/15384101.2015.1137714.
Alqadah, A., Hsieh, Y.-W., Schumacher, J.A., Wang, X., Merrill, S.A., Millington, G., Bayne, B*., Jorgensen, E.M., and Chuang, C.-F. (2016). SLO potassium channels couple gap junctions to inhibition of calcium signaling in olfactory neuron diversification. *Undergraduate student. PLoS Genetics 12(1): e1005654. doi:10.1371/journal.pgen.1005654.
2015
Alqadah, A., Hsieh, Y.-W., Vidal, B., Chang, C., Hobert, O., and Chuang, C.-F. (2015). Postmitotic diversification of olfactory neuron types is mediated by differential activities of the HMG-box transcription factor SOX-2. EMBO Journal 34, 2574-2589.
Vidal, B., Santella, A, Bao, Z., Chuang, C-F., and Hobert, O. (2015). C. elegans SoxB genes are dispensable for embryonic neurogenesis but required for terminal differentiation of specific neuron types. Development 142, 2464-2477.
2014
Alqadah, A., Hsieh, Y.-W., and Chuang, C.-F. (2014). A molecular link between distinct neuronal asymmetries. Cell Cycle 13, 1515-1516, doi: 10.4161/cc.29010.
Hsieh, Y.-W., Alqadah, A., and Chuang, C.-F. (2014). Asymmetric neural development in the Caenorhabditis elegans olfactory system. Invited review for the special issue on Left-right asymmetry: advances and enigmas. Genesis 52, 544-554. doi: 10.1002/dvg.22744.
Cochella, L., Tursun, B., Hsieh, Y.-W., Chuang, C.-F.*, and Hobert, O.* (2014). Two distinct types of neuronal asymmetries are controlled by the Caenorhabditis elegans zinc finger transcription factor die-1. *Senior authors contributed equally. Genes & Development 28, 34-43.
2013
Alqadah A., Hsieh, Y.W., and Chuang, C.-F. (2013). microRNA function in left-right neuronal asymmetry: perspectives from C. elegans. Frontiers in Cellular Neuroscience 7:158. doi:10.3389/fncel.2013.00158.
Zou, Y., Chiu, H., Zinovyeva, A., Ambros, V., Chuang, C.-F.*, and Chang, C*. (2013). Developmental decline in neuronal regeneration by the progressive change of two intrinsic timers in C. elegans. *Senior authors contributed equally. Science 340, 372-376.
2012
Schumacher, J.A., Hsieh, Y.-W., Chen, S., Pirri, J.K., Alkema, M.J., Li, W.-H., Chang, C., and Chuang, C.-F. (2012). Intercellular calcium signaling in a gap junction-coupled cell network establishes asymmetric neuronal fates in C. elegans. Development 139, 4191-4201.
Lobikin, M., Wang, G., Xu, J., Hsieh, Y.-W., Chuang, C.-F., Lemire, J.M., and Levin, M. (2012). Early, nonciliary role for microtubule proteins in left-right patterning is conserved across kingdoms. Proc. Natl. Acad. Sci. 109, 12586-91.
Hsieh, Y.-W., Chang, C., and Chuang, C.-F. (2012). The microRNA mir-71 inhibits calcium signaling by targeting the TIR-1/Sarm1 adaptor protein to control stochastic L/R neuronal asymmetry in C. elegans. PLoS Genetics 8, e1002864.
Zou, Y., Chiu, H., Domenger, D., Chuang, C.-F.*, and Chang, C*. (2012). The lin-4 microRNA targets the LIN-14 transcription factor to inhibit netrin-mediated axon attraction. *Senior authors contributed equally. Science Signaling 5, research article ra43.
2011
Chiu, H., Alqadah, A., Chuang, C.-F., and Chang, C (2011). C. elegans as a genetic model to identify novel cellular and molecular mechanisms underlying nervous system regeneration. Cell Adhesion & Migration 5, 387-394.
Chang, C., Hsieh, Y.-W., Bluma, J.L., Bargmann, C.I., and Chuang, C.-F. (2011). Microtubule-based localization of a synaptic calcium signaling complex specifies left-right neuronal asymmetry in C. elegans. Development 138, 3509-3518.
2010
Taylor, R., Hsieh, Y.-W.., Gamse, J., and Chuang, C.-F. (2010). Making a difference together: reciprocal interactions in C. elegans and zebrafish asymmetric neural development. Development 137, 681-691.
2008
Gabel, C. V., Antonie, F., Chuang, C.-F., Samuel, A. D., and Chang, C. (2008). Distinct cellular and molecular mechanisms mediate initial axon development and adult-stage axon regeneration in C. elegans. Development 135, 1129-1136.
Before 2008
Chuang, C.-F., VanHoven, M. K., Fetter, R. D., Verselis, V. K., and Bargmann, C. I. (2007). An innexin-dependent cell network establishes left-right neuronal asymmetry in C. elegans. Cell 129, 787-799.
Chuang, C.-F. and Bargmann, C. I. (2005). A Toll-interleukin 1 repeat protein at the synapse specifies asymmetric odorant receptor expression via ASK1 MAPKKK signaling. Genes & Development 19, 270-281.
Chuang, C.-F. and Meyerowitz, E. M. (2000). Specific and heritable genetic interference by double-stranded RNA in Arabidopsis thaliana. Proc. Natl. Acad. Sci. 97, 4985-4990. (Times cited: 1015)
Chuang, C.-F., Running, M. P., Williams, R. W., and Meyerowitz, E. M. (1999). The PERIANTHIA gene encodes a bZIP protein involved in the determination of floral organ number in Arabidopsis thaliana. Genes & Development 13, 334-344.
Full list of publications on PubMed
2024
Siete C. †, Xiong, R. †, Khalid, A.*, and Chuang, C.-F. (2024). Immobilization of C. elegans with different concentrations of an anesthetic for time-lase imaging of dynamic protein trafficking in neurons. microPublication Biology. 10.17912/micropub.biology.001069.
†These authors contributed equally to this work. *UIC undergraduate student.
2022
Xiong, R.†, Hsieh, Y.-W.†, and Chuang, C.-F. (2022). CEPsh glia development is not required for general AWC identity or AWC asymmetry. microPublication Biology. 10.17912/micropub.biology.000529.
†These authors contributed equally to this work.
Xiong, R., Hsieh, Y.-W., and Chuang, C.-F. (2022). mNG-tagged mls-2 knock-in alleles in C. elegans. microPublication Biology. 10.17912/micropub.biology.000529.
Hsieh, Y.-W. and Chuang, C.-F. (2022). Analysis of unc-62 expression pattern in C. elegans embryonic AWC neurons. microPublication Biology. 10.17912/micropub.biology.000530.
2021
Hsieh, Y.-W.†, Xiong, R.†, and Chuang, C.-F. (2021). Synergistic roles of homeodomain proteins UNC-62 homothorax and MLS-2 HMX/NKX in the specification of olfactory neurons in Caenorhabditis elegans. Genetics 219(2). doi: 10.1093/genetics/iyab133.
†These authors contributed equally to this work.
2019
Alqadah, A., Hsieh, Y.-W., Xiong, R., Lesch, B.J., Chang, C., and Chuang, C.-F. (2019). A universal transportin proteindiversifies olfactory neurons via specific nuclear import of a sox-2-activating factor. Proc. Natl. Acad. Sci. 116, 25137-25146.
2018
Chiu, H., Zou, Y., Suzuki, N., Hsieh, Y.-W., Chuang, C.-F., Wu, Y.-C., and Chang, C. (2018). Engulfing cellspromote neuronal regeneration and remove neuronal debris through distinct biochemicalfunctions of CED-1. Nature Communications 9. doi: 10.1038/s41467-018-07291-x.
Alqadah, A., Hsieh, Y.-W., Morrissey, Z., and Chuang, C.-F. (2018). Asymmetric development of the nervous system. Invited review for the special issue on development, disease and repair of the nervous system. Developmental Dynamics 247, 124-137. doi: 10.1002/dvdy.24595.
2017
Hsieh, Y.-W., Alqadah, A., and Chuang, C.-F. (2017). Mechanisms controlling diversification of olfactory sensory neuron classes. Invited review for Cellular and Molecular Life Sciences. doi:10.1007/s00018-017-2512-2.
Oh, K.H., Haney, J.J., Wang, X., Chuang, C.-F., Richmond, J.E., and Kim, H. (2017). ERG-28 controls BK channel trafficking in the ER to regulate synaptic function and alcohol response in C. elegans. eLife 2017;6:e24733. doi: http://dx.doi.org/10.7554/eLife.24733
2016
Hsieh, Y.-W., Alqadah, A., and Chuang, C.-F. (2016). An optimized protocol for electrophoretic mobility shift assay using infrared fluorescent dye-labeled oligonucleotides. Journal of Visualized Experiments 117: e54863. doi:10.3791/54863
Alqadah, A., Hsieh, Y.-W., Xiong, R., and Chuang, C.-F. (2016). Stochastic left-right neural asymmetry in C. elegans. Invited review for the special issue on left-right asymmetries of pattern formation: integrating chiral information from cells to organisms. Philosophical Transactions of the Royal Society B 371: 20150407. doi: 10.1098/rstb.2015.0407.
Alqadah, A., Hsieh, Y.-W., and Chuang, C.-F. (2016). Sox2 goes beyond stem cell biology. Cell Cycle 15, 777-778, doi: 10.1080/15384101.2015.1137714.
Alqadah, A., Hsieh, Y.-W., Schumacher, J.A., Wang, X., Merrill, S.A., Millington, G., Bayne, B*., Jorgensen, E.M., and Chuang, C.-F. (2016). SLO potassium channels couple gap junctions to inhibition of calcium signaling in olfactory neuron diversification. *Undergraduate student. PLoS Genetics 12(1): e1005654. doi:10.1371/journal.pgen.1005654.
2015
Alqadah, A., Hsieh, Y.-W., Vidal, B., Chang, C., Hobert, O., and Chuang, C.-F. (2015). Postmitotic diversification of olfactory neuron types is mediated by differential activities of the HMG-box transcription factor SOX-2. EMBO Journal 34, 2574-2589.
Vidal, B., Santella, A, Bao, Z., Chuang, C-F., and Hobert, O. (2015). C. elegans SoxB genes are dispensable for embryonic neurogenesis but required for terminal differentiation of specific neuron types. Development 142, 2464-2477.
2014
Alqadah, A., Hsieh, Y.-W., and Chuang, C.-F. (2014). A molecular link between distinct neuronal asymmetries. Cell Cycle 13, 1515-1516, doi: 10.4161/cc.29010.
Hsieh, Y.-W., Alqadah, A., and Chuang, C.-F. (2014). Asymmetric neural development in the Caenorhabditis elegans olfactory system. Invited review for the special issue on Left-right asymmetry: advances and enigmas. Genesis 52, 544-554. doi: 10.1002/dvg.22744.
Cochella, L., Tursun, B., Hsieh, Y.-W., Chuang, C.-F.*, and Hobert, O.* (2014). Two distinct types of neuronal asymmetries are controlled by the Caenorhabditis elegans zinc finger transcription factor die-1. *Senior authors contributed equally. Genes & Development 28, 34-43.
2013
Alqadah A., Hsieh, Y.W., and Chuang, C.-F. (2013). microRNA function in left-right neuronal asymmetry: perspectives from C. elegans. Frontiers in Cellular Neuroscience 7:158. doi:10.3389/fncel.2013.00158.
Zou, Y., Chiu, H., Zinovyeva, A., Ambros, V., Chuang, C.-F.*, and Chang, C*. (2013). Developmental decline in neuronal regeneration by the progressive change of two intrinsic timers in C. elegans. *Senior authors contributed equally. Science 340, 372-376.
2012
Schumacher, J.A., Hsieh, Y.-W., Chen, S., Pirri, J.K., Alkema, M.J., Li, W.-H., Chang, C., and Chuang, C.-F. (2012). Intercellular calcium signaling in a gap junction-coupled cell network establishes asymmetric neuronal fates in C. elegans. Development 139, 4191-4201.
Lobikin, M., Wang, G., Xu, J., Hsieh, Y.-W., Chuang, C.-F., Lemire, J.M., and Levin, M. (2012). Early, nonciliary role for microtubule proteins in left-right patterning is conserved across kingdoms. Proc. Natl. Acad. Sci. 109, 12586-91.
Hsieh, Y.-W., Chang, C., and Chuang, C.-F. (2012). The microRNA mir-71 inhibits calcium signaling by targeting the TIR-1/Sarm1 adaptor protein to control stochastic L/R neuronal asymmetry in C. elegans. PLoS Genetics 8, e1002864.
Zou, Y., Chiu, H., Domenger, D., Chuang, C.-F.*, and Chang, C*. (2012). The lin-4 microRNA targets the LIN-14 transcription factor to inhibit netrin-mediated axon attraction. *Senior authors contributed equally. Science Signaling 5, research article ra43.
2011
Chiu, H., Alqadah, A., Chuang, C.-F., and Chang, C (2011). C. elegans as a genetic model to identify novel cellular and molecular mechanisms underlying nervous system regeneration. Cell Adhesion & Migration 5, 387-394.
Chang, C., Hsieh, Y.-W., Bluma, J.L., Bargmann, C.I., and Chuang, C.-F. (2011). Microtubule-based localization of a synaptic calcium signaling complex specifies left-right neuronal asymmetry in C. elegans. Development 138, 3509-3518.
2010
Taylor, R., Hsieh, Y.-W.., Gamse, J., and Chuang, C.-F. (2010). Making a difference together: reciprocal interactions in C. elegans and zebrafish asymmetric neural development. Development 137, 681-691.
2008
Gabel, C. V., Antonie, F., Chuang, C.-F., Samuel, A. D., and Chang, C. (2008). Distinct cellular and molecular mechanisms mediate initial axon development and adult-stage axon regeneration in C. elegans. Development 135, 1129-1136.
Before 2008
Chuang, C.-F., VanHoven, M. K., Fetter, R. D., Verselis, V. K., and Bargmann, C. I. (2007). An innexin-dependent cell network establishes left-right neuronal asymmetry in C. elegans. Cell 129, 787-799.
Chuang, C.-F. and Bargmann, C. I. (2005). A Toll-interleukin 1 repeat protein at the synapse specifies asymmetric odorant receptor expression via ASK1 MAPKKK signaling. Genes & Development 19, 270-281.
Chuang, C.-F. and Meyerowitz, E. M. (2000). Specific and heritable genetic interference by double-stranded RNA in Arabidopsis thaliana. Proc. Natl. Acad. Sci. 97, 4985-4990. (Times cited: 1015)
Chuang, C.-F., Running, M. P., Williams, R. W., and Meyerowitz, E. M. (1999). The PERIANTHIA gene encodes a bZIP protein involved in the determination of floral organ number in Arabidopsis thaliana. Genes & Development 13, 334-344.